存储，保护和提供对基因组数据的Petabytes的访问

Genomics England has ambitious aims. The organization was established in 2013 by the UK’s Department of Health & Social Care to sequence the genomes of 100,000 people, generating new insights that can help improve treatments—while also accelerating the development of the UK genomics industry. In 2018, the project was significantly expanded: the new goal was to sequence up to five million genomes over five years.

遗憾的是，用于存储基因组数据的现有网络附加存储（NAS）解决方案是为了完成任务。持有21个数据的NAS达到了其节点缩放限制。“我们需要一些比现有的NAS解决方案更具可扩展 - 一个可以长到数百个Petabytes的基础设施，”基因组学英格兰的技术送货主管大卫娱乐说。新的解决方案还必须通过超过3,000多个研究人员促进简单，灵活地访问数据。

Using Quantum ActiveScale Object Storage
Genomics England called on Nephos Technologies, an independent UK-based data services organization, to design and implement a new storage solution. Together, teams from Nephos and Genomics England deployed a multi-faceted solution that incorporates a WekaIO high-performance file system, Mellanox high-speed networking, and ActiveScale object storage.

The solution creates a two-tier architecture that combines flash storage plus ActiveScale object storage system, which serves as a long-term data lake repository. The two storage tiers—each of which can be scaled independently—present as a single hybrid storage environment. As a result, researchers have the flexibility to query data in a highly randomized fashion.

在Covid-19流行期间承担新挑战
在部署新存储环境的几年内，基因组学英格兰需要再次扩展。2020年初的Covid-19流行病的出现为全球医学科学界提出了新的，紧迫的挑战，而英格兰的基因组学是在鼎盛的位置，以帮助更好地理解谁易受病毒的影响。该组织致力于测序高达20,000名密集护理患者的Covid-19加上最多15,000人的基因组，病毒仅经历轻微症状。

Around the same time that Genomics England was ramping up participation in COVID-19 research, the ActiveScale solution platform was acquired by Quantum. A Quantum team facilitated a smooth transition for Genomics England, which expanded the object-storage environment from 40 PB to more than 100 PB.

缩放与RAID（冗余独立磁盘阵列）无缝。“我们对活动系统所爱的是，其固有的架构是由其RAID替换技术，智能，动态放置的擦除编码数据的造成基础，”Ardley说。动态展示位置消除了对系统重新平衡的需求，这可能会损害性能和可用性。

Protecting Vital Genomic Data
ActiveScale对亚搏电竞app下载象存储保护数据并提供基因组学英格兰对其关键工作需求的数据弹性。该组织利用了ActiveScale的地理分布式能力。使用ActivEscale，组织在三个数据中心分发数据，用于对诸如网站丢失等重大灾难的全数据保护。

控制成本和复杂性的同时获得可扩展性
随着ActiveScale，Genomics英格兰不再面临其先前NAS解决方案的容量限制。该组织扩展了其对象存储，以支持更多的基因组分析，并在额外的Covid亚搏电竞app下载-19工作中进行，而无需重大存储大修。

This scalable storage environment also helps reduce costs. According to Nephos, the Genomics England team decreased storage costs by 75 percent per genome compared with the previous environment. The organization is expected to reduce costs by 96 percent by 2023.

Just as important, the Genomics England team has experienced these benefits without adding complexity. The new integrated storage environment makes it simple for researchers from around the world to store and access the genomic data they need for their work.